KMID : 0384119940140040385
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Korean Journal of Clinical Pathology 1994 Volume.14 No. 4 p.385 ~ p.390
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Essential Thrombocythemia in a Child
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Abstract
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Essential thrombocythemia is uncommon disorder and characterized by abnormal proliferation of the megakaryocytes. It has been seen most commonly in middle age and rare I children. The criteria for diagnosis of essential thrombocythemia were based
on the
definition reported by the Polycythemia Vera Study Group.
We experienced a case of essential thrombocythemia in a 14-year-old boy presented with headache, periorbitla pain, nausea and vomiting for 3 days. Hepatosplenomegaly was found. Platelet counts of the peripheral blood was 2.403x10E9/L. The
underlying
disease for a thrombocytosis had not been detected. Platelet aggregation test showed no response to epinephrine and ristocetin and decreased response without secondary wave to ADP. Bone marrow biopsy and aspiration revealed hyperplasia of
megakaryocytes.
We report a case of essential thrombocythemia in a child with the review of literature.
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KEYWORD
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